凌云,裴新军.多发伤患者早期应激并发症危险因素分析[J].内科急危重症杂志,2015,21(4):
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| DOI： |
| 中文关键词: 多发伤 应激 并发症 危险因素 回归分析 |
| 英文关键词:multiple trauma stress complication Risk factor Logistic regression |
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| 中文摘要: |
| 目的 探讨多发伤患者早期应激并发症的危险因素。 方法 收集2011年10月～2013年6月由急诊收入重症监护病房(ICU)住院的64例多发伤患者的病例资料,对相关的因素进行单因素及多因素的Logistic 回归分析。 结果 48例患者出现应激性溃疡、急性呼吸窘迫综合症等应激并发症,单因素回归分析表明,急性生理和慢性健康评分(APACH II)、血皮质醇、促肾上腺皮质激素(ACTH)、三碘甲状腺原氨酸(TT3)、游离三碘甲状腺原氨酸(FT3)、甲状腺素(TT4)、白介素-1(IL-1)、白介素-6(IL-6)、白介素-8(IL-8)、白介素-10(IL-10)、肿瘤坏死因子(TNFα)差异有统计学意义(P<0.05)；多因素Logistic分析表明,APACH II评分、TT4、皮质醇、IL-6、IL10、TNFα为早期应激并发症的独立危险因素。 结论 多发伤患者APACH II评分以及TT4、皮质醇、IL6、IL10、TNFα等指标的变化与患者应激性消化道出血及呼吸窘迫综合症等应激并发症的出现呈密切相关。 |
| 英文摘要: |
| Objective To investigate the risk factors for early stress complication in multiple trauma patients. Methods Clinical data were collected from 64 hospitalized patients admitted to ICU from Oct.2011 to Jun.2013, the related factors for multiple trauma patients were statistically analyzed by univariate and multivariate binary Logistic regression. Results 48 patients occurred stress complication e.g.Stress ulcer、Acute Respire Distress Syndrome(ARDS), 10 factors such as APACH II grade、Cortisol、ACTH、TT3、FT3、TT4、IL-6、IL-8、IL-10、TNFα had significant difference(P<0.05). By multivariate analysis in which APACH II grade、Cortisol、TT4、IL-6、IL-10、TNFa were the independent risk factors for stress complication. Conclusion The change of APACH II grade、COR、TT4、IL-6、IL-10、TNFa were apparently correlated with stress complication occurred in multiple trauma patients. |
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