张欣,赵子平.急性呼吸窘迫综合征小潮气量肺保护通气策略的预后分析[J].内科急危重症杂志,2015,21(21):
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| DOI： |
| 中文关键词: 急性呼吸窘迫综合征 肺保护性通气策略 通气 小潮气量 |
| 英文关键词:Acute respiratory distress syndrome lung protective ventilation strategies ventilation small tidal volume |
| 基金项目:河北省卫生厅课题：无创正压通气在拔管后呼吸衰竭中的应用，编号：20130438 |
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| 中文摘要: |
| 目的：探讨急性呼吸窘迫综合征应用小潮气量肺保护性通气策略的预后情况。方法：急性呼吸窘迫综合征患者80例根据入住病床单双号分为治疗组40例与对照组40例,两组都给予常规治疗,治疗组采用小潮气量辅助/控制机械通气治疗,对照组采用肺复张/机械通气治疗。结果：两组治疗前Pa02、Pa02/Fi02和PaC02对比无明显差异,治疗后各时间点Pa02和Pa02/Fi02值明显上升,PaC02值显下降(P<0.05),同时组间对比无统计学差异。治疗组的机械通气时间与住院时间都明显少于对照组,差异有统计学意义(P<0.05)。两组都无死亡患者,治疗组呼吸机相关肺炎、恶心呕吐和肺出血并发症发生率明显低于对照组(P<0.05)。结论：小潮气量肺保护性通气策略应用于呼吸窘迫综合征的治疗能有效保持动脉血气的稳定,加快患者的恢复,减少并发症,值得推广应用。 |
| 英文摘要: |
| The prognosis analysis of small tidal volume noninvasive lung protective ventilation strategies for acute respiratory distress syndrome#$NL: Objective: To investigate the prognosis of small tidal volume noninvasive lung protective ventilation strategies for treating acute respiratory distress syndrome. Methods: 80 cases of acute respiratory distress syndrome accorded the odd and even numbers of beds were equally divided into the treatment group and the control group, two groups were given conventional treatment, and the treatment group were uesed low tidal volume assist / control mechanical ventilation, the control group were given lung recruitment / mechanical ventilation. Results: The Pa02, Pa02/Fi02 and PaC02 values between two groups before treatment compared had no significant differences, and the Pa02 and Pa02/Fi02 values were increased significantly after treatment at all time points, PaC02 values were decreased significantly (P <0.05), while there had no statistically significant between the two groups compared. The mechanical ventilation time and hospital stay of the treatment group were significantly less than the control group (P <0.05). there were no deaths in both groups, but the ventilator-associated vomiting and pulmonary hemorrhage overall complication rate of the treatment group were significantly lower than the control group (P <0.05). Conclusion: Noninvasive low tidal volume lung protective ventilation strategy applied pediatric respiratory distress syndrome can effectively maintain the stability of arterial blood gases, accelerate the recovery , reduce complications that should be widely applied.#$NLKeywords: Acute respiratory distress syndrome; lung protective ventilation strategies; ventilation; small tidal volume |
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