贺冠强.化疗致非霍奇金淋巴瘤患者乙肝病毒再激活研究进展贺冠强* 郭敏(综述) 陈海林(审校)[J].内科急危重症杂志,2015,21(5):
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| DOI： |
| 中文关键词: 乙肝病毒 化疗 再激活 非霍奇金淋巴瘤 |
| 英文关键词:Hepatitis B virus Chemotherapy Reactivation Non-Hodgkin Lymphoma |
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| 中文摘要: |
| 乙肝病毒再激活为患者体内ＨＢＶ-ＤＮＡ出现复制,血清中ＨＢＶ-ＤＮＡ水平增加。ＨＢＶ 再激活临床表现呈多样性,轻者可为临床症状的单纯 ＨＢＶ-ＤＮＡ 水平升高,重者可以出现活动性肝病的临床表现,甚至出现爆发性肝炎,进而引起肝功能衰竭而死亡。乙肝病毒再激活不仅可以发生在HbsAg阳性患者,对于HbsAg阴性/anti-HBc阳性患者亦可发生HBV再激活,本文将就化疗致非霍奇金淋巴瘤患者HBV再激活情况展开综述。 |
| 英文摘要: |
| Reactivation of hepatitis B refers to the abrupt increase in hepatitis B virus (HBV) replication in a patient with inactive or resolved hepatitis B. Clinical manifestations of hepatitis B reactivation are variable and can range from asymptomatic to acute hepatitis, which are sometimes serious and result in acute liver failure with risk of death。chemotherapy can induce HBV reactivation in patients not only carrying hepatitis B virus surface antigen (HBsAg) but also anti-HBc( )。HBV reactivation is triggered by chemotherapy in Non-Hodgkin Lymphoma is to be reviewed here. |
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