• 枸橼酸钠在CRRT抗凝中补钙速率探讨叶涛1 余追2
  • To investigate the infusion speed of calcium in regional citrate anticoagulation with CRRTYE Tao,Yu Zhuii,. ICU, Aikang hospital,Hubei Huangshi,435000,china
  • 叶涛.枸橼酸钠在CRRT抗凝中补钙速率探讨叶涛1 余追2[J].内科急危重症杂志,2016,22(2):
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    中文关键词:  局部枸橼酸抗凝  CRRT  
    英文关键词:regional citrate anticoagulation  continuous rental replacement therapy  calcium
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    作者单位E-mail
    叶涛 黄石市爱康医院ICU yetao5881@163.com 
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    中文摘要:
          目的 探讨CRRT中用枸橼酸钠抗凝补钙的速率。方法 (1)45例CRRT治疗用枸橼酸钠抗凝的病人随机分成3组,三组患者给予不同速率10%葡萄糖酸钙:1组 补钙速率为11ml/h[1](枸橼酸钙结合量)相当于枸橼酸速率6.1%, 2组:补钙速率为22.5ml/h[2],相当于置换液的钙含量, 3组采用置换液钙含量+枸橼酸钙结合量 33.5ml/h[3]。间隔2h测钙离子。(2)三组患者给予不同置换液r容量,测滤器前血清离子钙。结果 (1)2h后,1组血液钙离子显著降低,3组血液钙离子高于正常值,2组2h后血钙正常,4h,8h保持稳定。(2)置换量不同,钙需要量不同。结论 用枸橼酸抗凝,通过置换液量调整补钙速率是较为准确的方法,可作为调整补钙速率的重要参考依据。
    英文摘要:
          【】Objective To investigate the infusion speed of calcium in regional citrate anticoagulation(RCA) with continuous rental replacement therapy (CRRT) Methods (1)45 cases were selected randomly into 3 groups, were inputted the venous with the different infusion speed of calcium. Group 1:The infusion speed of calcium is 11ml/h(equal to 6.1% velocity of citrate). Group 2:The infusion speed of calcium is 22.5ml/h(equal to calcium content of substitute liquid).. Group 3:The infusion speed of calcium is 33.5ml/h(equal to Group 1 Group 2). (2) Monitoring the calcium content with substitute liquid capacity.. Results :(1) After 2 hours, the calcium level of group 1 decrease;The calcium level of group 3 increase;The calcium level of group 2 is stable, After 4 hours and 6 hours, the calcium level of group 2 remain stable.(2) The calcium ion concentration is different with substitute liquid capacity. Conclusions The infusion speed of calcium is adjusted by substitute liquid capacity, which is important reference index.