吴崑,严红丽,冉然.三叉神经痛患者应用罗哌卡因、维生素B12联合复方倍他米松治疗的临床效果研究[J].内科急危重症杂志,2016,22(5):
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| DOI： |
| 中文关键词: 复方倍他米松 维生素B12 罗哌卡因 三叉神经痛 |
| 英文关键词:compound betamethasone vitamin B12 ropivacaine prosopalgia |
| 基金项目:2013年湖北省自然科学基金项目：背根神经节局部GAT-3调控对神经痛的治疗作用及其分子机制，编号：2013CFC036 |
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| 中文摘要: |
| 目的：探究三叉神经痛患者应用罗哌卡因、维生素B12联合复方倍他米松治疗的临床效果。 方法：选取2014年1～12月的80例本院收治的原发性三叉神经痛患者为研究对象，并随机等分为实验组及对照组各40例。其中实验组患者应用罗哌卡因、维生素B12联合复方倍他米松治疗，而对照组应用单纯罗哌卡因治疗。分析比较两组患者治疗后第3、6及9个月的临床效果。结果：比较第3、6及9个月时两组的治疗效果，实验组的总有效率明显高于对照组，差异有统计学意义（P=0.045,0.032, 0.008）。其中治疗期间实验组中有4例患者出现了黏膜破损的状况，并在治疗完成时恢复正常。实验组中有3例患者在治疗后发生下唇感觉迟钝的情况，与健侧无异。结论：三叉神经痛患者应用复方倍他米松、维生素B12联合罗哌卡因的临床疗效明显优于单纯罗哌卡因疗法。 |
| 英文摘要: |
| Objective: To explore the clinical effect of ropivacaine, vitamin B12 combined with compound betamethasone on patients with prosopalgia. Methods: Select 80 patients with prosopalgia from January 2014 to December 2014 as research subjects. And the research subjects were random divided into experimental group and control group. The experimental group received compound betamethasone, vitamin B12 combined with ropivacaine, while the control group received ropivacaine only. The clinical effect was compared between the two groups 3,6 and 9 months after the treatment. Results: The total effective rate of experimental group was observably higher than the control group 3,6 and 9 months after the treatment (P=0.045,0.032,0.008). There were 4 patients whose mucous membrane was broken in experimental group during the treatment. And there were 3 patients whose underlips were insensitive in experimental group after the treatment. Conclusion: The clinical effect of ropivacaine, vitamin B12 combined with compound betamethasone on patients with prosopalgia was observably better than ropivacaine alone. |
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