李瑾.重症肌无力胸腺切除术后发生肌无力危象的危险因素分析[J].内科急危重症杂志,2016,22(4):
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| DOI： |
| 中文关键词: 重症肌无力 胸腺切除术 危险因素 术后肌无力危象 |
| 英文关键词:Myasthenia Gravis, Thymectomy, Risk factors, Postoperative myasthenic crisis |
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| 中文摘要: |
| 目的:回顾性分析研究重症肌无力患者胸腺切除术后发生肌无力危象的危险因素。
方法:对本医院1970年-2011年实施的胸腺切除术的306例MG患者进行回顾分析，利用Logistic回归从多种相关因素（例如年龄、分型、术前术后处理、手术方式、预后等）中筛选出危险因素。
结果:术后发生肌无力危象与患者发病年龄、手术时间、病程、术前分型、术前是否累及吞咽肌、术前是否发生危象、是否确定为胸腺瘤相关，并且关系着患者的预后。
结论:术前吞咽肌受累、术前发生危象、确诊胸腺瘤是预测胸腺切除术后肌无力危象发生的独立危险因素。 |
| 英文摘要: |
| Objective: To analyze risk factors for postoperative myasthenic crisis after thymectomy in MG patients.
Methods:An retrospective analysis was launched in 306 MG patients who had undergone thymectomy from May,1970 to May,2011.Risk factors were screened by multivariate logistic regression analysis among several relevant factors such as age, subtypes, pre- or post-operative treatments, operation methods, prognosis, etc.
Results:Postoperative myasthenic crisis, PMC is related to onset age, operation age, clinical course, MGFA subtypes, preoperative bulbar symptoms, preoperative myasthenic crisis, thymoma. And PMC indeed matters prognosis of MG patients.
Conclusion:Preoperative bulbar symptoms, preoperative myasthenic crisis and thymoma are three independent risk factors for PMC. |
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