• 急性心肌梗死患者住院期间平均血钾水平和预后之间的关系
  • Relation of Serum Potassium Level to Outcomes in Patients With Acute Myocardial Infarction
  • 程澜.急性心肌梗死患者住院期间平均血钾水平和预后之间的关系[J].内科急危重症杂志,2017,23(2):
    DOI:
    中文关键词:  急性心肌梗死,血钾,死亡率
    英文关键词:acute myocardial infarction (AMI), serum potassium level, mortality
    基金项目:
    作者单位E-mail
    程澜 武汉亚洲心脏病医院 471907791@qq.com 
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    中文摘要:
          目的:探讨急性心肌梗死患者住院期间平均血钾水平与3年后死亡率之间的关系,从而为这类患者应维持的最佳血钾水平提供临床依据。方法:武汉亚洲心脏病医院2012年01月至2013年01月进入急诊系统的1190例急性心肌梗死患者纳入本研究,根据其平均血钾浓度分为五组:<3.5,3.5-4.0,4.0-4.5,4.5-5.0,>5.0mmol/L。用Cox回归分析比较3年后死亡率。结果:患者平均随访时间3.12±1.24年。血钾3.5-4.0mmol/L组死亡率最低。结论:目前再灌注治疗和以循证医学为基础的药物治疗已常规应用,可能现代急性心肌梗死患者的理想血钾水平是3.5-4.0mmol/L之间。
    英文摘要:
          Objectives: This study is to explore the relation of the average serum potassium levels measured throughout the hospitalization to 3-year mortality in patients with acute myocardial infarction(AMI). Therefore, it provides the clinical basic on the ideal serum potassium level in patients with AMI. Methods: A total of 1190 patients who were admitted to the emergency department of Wuhan Asia Heart Hospital from January 2012 to January 2013 with a diagnosis of AMI were evaluated retrospectively. Patients were categorized into 5 groups according to the average serum potassium levels: <3.5,3.5-4.0,4.0-4.5,4.5-5.0,>5.0mmol/L. Cox proportional regression analysis was used to compare 3-year mortality by categories of mean serum potassium level. Results: The patients were followed up for a mean period of 3.12±1.24 years. The mortality was lowest in the group of patients with potassium levels of 3.5 to <4.0 mmol/L. Conclusions: Modern AMI management strategies, incorporating reperfusion therapy and evidence-based medications, are in routine use. Currently, it is possible that the ideal serum potassium level in patients with AMI is from 3.5 to <4.0 mmol/L.