郭晓贤,郝美美,贺亚龙,范百亚,康静.交感神经皮肤反应与神经传导测定对糖尿病周围神经病变的诊断价值[J].内科急危重症杂志,2017,23(3):
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| 中文关键词: 2型糖尿病 糖尿病周围神经病变 交感神经皮肤反应 运动神经传导速度 感觉神经传导速度 诊断 |
| 英文关键词:Type 2 diabetes Diabetic peripheral neuropathy. Sympathetic skin response Motor nerve conduction velocity Sensory nerve conduction velocity Diagnosis |
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| 中文摘要: |
| [摘要]目的 分析比较交感神经皮肤反应与神经传导速度对糖尿病周围神经病变的诊断价值。方法 选取本院2014年1月-2015年12月门诊收治的43例2型糖尿病患者和43例健康体检者，同时行神经电图检测，包括感觉神经传导速度、运动神经传导速度和交感神经皮肤反应，并对结果进行记录和统计学分析。结果 糖尿病组的正中神经、尺神经、腓总神经、胫神经的运动神经传导速度和正中神经、尺神经、腓肠神经、腓浅神经的感觉神经传导速度均明显低于健康组（P＜0.01）；健康组上下肢的起始潜伏期均明显少于糖尿病组（P＜0.01），但糖尿病组上下肢的波幅与健康组相比较，差异均无统计学意义（P＞0.05）；糖尿病组患者的下肢的神经传导速度的异常率（34.84%）明显高于上肢（18.85%），两者差异存统计学意义（χ2=16.97,P＜0.01）；上肢的交感神经皮肤反应异常率（35.24%）低于下肢（55.74%），差异存统计学意义（χ2=10.33,P＜0.01）；神经传导速度和交感神经皮肤反应总异常率分别为25.58%、45.49％，交感神经皮肤反应的总异常率显著高于神经传导速度，差异存统计学意义（χ2=39.96,P＜0.01）。 结论 神经传导速度和交感神经皮肤反应作为糖尿病自主神经及周围神经病变诊断的重要指标，可为糖尿病周围神经病的早期诊断提供重要依据，且交感神经皮肤反应对糖尿病周围神经病早期诊断的敏感性更高。 |
| 英文摘要: |
| [Abstract] Objective To analysis the value of sympathetic skin response and electroneurograms in diagnosing diabetic peripheral neuropathy. Method The electroneurophysiological data on 43 cases of 2 diabetes and 43 cases of healthy people in our hospital between January 2013 and December 2015,including sensory nerve conduction velocity(SCV) data,motor nerve conduction velocity(MCV) data and sympathetic skin response(SSR)data,were analyzed retrospectively. Result The MCV of median nerve,ulnar nerve and nervous peroneus communis and the SCV of median nerve ,ulnar nerve and sural nerve in diabetes mellitus group were significantly lower than the control group(P＜0.01＝.The upper and lower extremities initial incubation period of the study group was significantly longer than that healthy group(P＜0.01＝,while the difference of amplitude was not statistically significant (P＞0.05).The abnormal rate of nerve conduction velocity of lower limbs in patients with diabetes mellitus was 34.84%,which was significantly higher than those of upper limbs.The difference was statistically significant (chi-square = 16.97, P < 0.01).The abnormal rate of sympathetic skin response of upper limbs was 35.24%,which was lower than the lower limbs.The difference was statistically significant (chi-square = 10.33, P < 0.01).The total abnormal rate of Nerve conduction velocity was 25.58%.And the same rate of sympathetic skin response was 45.49%,which was significantly higher than that of nerve conduction velocity.The difference was statistically significant (chi-square = 39.96, P < 0.01). Conclusion Nerve conduction velocity and sympathetic skin response are sensitive indices for the diagnosis of diabetic peripheral neuropathy,and can provide important evidence for the early diagnosis.Sympathetic skin response could be more sensitive to early diagnosis of diabetic peripheral neuropathy. |
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