• 嗜水气单胞菌致脓毒性休克1例报告并文献复习
  • Septic shock due to aeromonas hydrophila:a case report and literature review
  • 赖勋耀,俞洋,王华,岑仲然,余英典,周健.嗜水气单胞菌致脓毒性休克1例报告并文献复习[J].内科急危重症杂志,2017,23(3):
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    中文关键词:  嗜水气单胞菌  坏死性筋膜炎  脓毒性休克
    英文关键词:aeromonas hydrophila  necrotizing fasciitis  severe septic shock
    基金项目:广东省省级科技计划项目(2014A020212670)
    作者单位E-mail
    赖勋耀 广东省英德市人民医院 laixunyao@163.com 
    俞洋 广东省英德市人民医院  
    王华 南方医科大学珠江医院  
    岑仲然 南方医科大学珠江医院 cenzhr2014@163.com 
    余英典 南方医科大学珠江医院  
    周健 南方医科大学珠江医院  
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    中文摘要:
          嗜水气单胞菌是多种水生动物的原发性致病菌,引起人体感染的病例报道逐渐增多,由于临床医师不熟悉其临床表现、细菌学诊断滞后和阳性率低等因素易导致误诊误治,病情进展迅速,致残率和致死率高。本文结合一例2型糖尿病患者因嗜水气单胞菌感染致坏死性筋膜炎并发脓毒性休克的成功救治体会,复习相关文献,旨在总结该菌的致病特点以及探讨防治方法,以供临床参考,提高救治成功率。
    英文摘要:
          A 66-year-old male patient with type 2 diabetes mellitus presented severe septic shock and necrotizing fasciitis (NF) caused by aeromonas hydrophila (AH), empirical antimicrobial therapy was given at the beginning and then shifted to target-oriented antibiotic treatment, and pulse indicator continuous cardiac output monitoring (PiCCO) combined with continuous renal replacement therapy (CRRT) were applied for toxin clearance and fluid balance, surgical interventions were also instituted timely. After treatment, infectious index decreased significantly, vasoactive drugs rapidly tapered to discontinuation, and the affected limb was preserved. Follow-up visit found the limb function was gradually restored with well-grown grafted skin.