成人暴发性心肌炎不同治疗方案差异分析
Statistical analysis on differences in different treatments for adults with fulminant myocarditis

苗琨.成人暴发性心肌炎不同治疗方案差异分析[J].内科急危重症杂志,2017,23(6):465-468

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DOI：10.11768/nkjwzzzz20170607

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作者	单位	E-mail
苗琨	华中科技大学同济医学院附属同济医院	jiangjg618@126.com

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中文摘要:

目的：调查成人暴发性心肌炎(FM)的临床特点及不同治疗方式对预后的影响，为临床诊治及预后评估提供参考。方法：回顾性分析83例成人FM患者的临床资料。根据治疗方式分为传统治疗组（47例）和生命支持治疗组（36例）。统计不同治疗方案与终点事件（院内死亡、存活患者的住院时间）的差异。结果：传统治疗组院内病死率明显高于生命支持治疗组（59.6% vs 5.6%,P<0.01），且生命支持组患者平均住院时间较普通治疗组有所减少（12.5d vs 14d, P<0.05）。结论:成人FM患者应尽早采取“以生命支持为依托的综合治疗方案”进行救治。

英文摘要:

Objective: To investigate the clinical features and prognostic factors in adults with fulminant myocarditis (FM). Methods: The clinical data of 83 adults with FM were retrospectively analyzed. According to the treatment, these patients were classified into two groups: traditional treatment group (n=47) and life support treatment group (n=36). The association between endpoints (in-hospital death and hospital stay of the surviving patients) and the different treatments was analyzed. Results: The in-hospital mortality in traditional treatment group was significantly higher than that in life support treatment group ( 59.6% vs 5.6%, P<0.01). The average time of hospitalization in life support group was shorter than traditional treatment group (12.5d vs 14d,P＜0.05). Conclusions: Patients with FM should be treated with life support-based comprehensive treatment regimen as early as possible.