李清,陈玉华.伴有卵圆孔未闭的神经内科疾病的临床观察分析[J].内科急危重症杂志,2017,23(5):
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| DOI： |
| 中文关键词: 卵圆孔未闭 偏头痛 脑卒中 脑白质病 晕厥 不明原因 |
| 英文关键词:patent foramen ovale migraine stroke Leukoencephalopathy syncope cryptogenic |
| 基金项目:湖北省卫生计生委科研项目（WJ2017F057) |
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| 中文摘要: |
| 摘要：目的 分析伴卵圆孔未闭( patent foramen ovale, PFO)的神经内科疾病的类型和发病机制。方法 对2015 年 12月—2016 年 12 月来我院就诊的24例伴 PFO的神经内科疾病的临床资料进行回顾性 分析。 结果 24例中16 例为偏头痛, 16例中有3例偏头痛合并脑白质病变。4例为不明原因的脑卒中，2例为不明原因的脑白质病，2例为不明原因的晕厥。其中为右向左分流量大的4例患者，均给予PFO 封堵术治疗; 随访 3 个月, 病情完全缓解, 未复发。 结论 PFO与神经内科疾病关系密切，其主要发病机制可能为反常栓塞。经皮卵圆孔封堵术治疗偏头痛、脑白质病和减少不明原因脑卒中、晕厥的复发是有效的。 |
| 英文摘要: |
| Abstract: Objective To explore the clinical features and pathogenesis of neurological diseases accompanied with the patent foramen ovale (PFO). Methods The clinical data of 24 neurological diseases accompanied with PFO were analyzed retrospectively. Results Of the 24 patients included, sixteen patients were diagnosed with migraine, and three of them have white matter lesions (WML). Four patients were diagnosed with cryptogenic stroke. Two patients were diagnosed with cryptogenic Leukoencephalopathy. Two patients were diagnosed with unexplained syncope. Among them, 4 patients with large right-to-left shunt underwent the interventional closure and were followed up for 3 months, all were completely recovered, none with episodes again. Conclusion PFO is highly correlated with neurological diseases, its pathogenesis of PFO may be paradoxical embolism. Interventional closure is an efficient method for neurological diseases with PFO. |
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