• 合并右心衰竭对慢性阻塞性肺疾病急性加重频率及严重程度的影响
  • Influence of right heart failure on the frequency and severity of acute exacerbations of chronic obstructive pulmonary disease
  • 林祥兵.合并右心衰竭对慢性阻塞性肺疾病急性加重频率及严重程度的影响[J].内科急危重症杂志,2019,25(1):45-47
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    DOI:10.11768/nkjwzzzz20190114
    中文关键词:  慢性阻塞性肺疾病  急性加重  右心衰竭
    英文关键词:
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    作者单位E-mail
    林祥兵 合肥市第一人民医院 imdzh@163.com 
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    中文摘要:
          目的:探讨合并右心衰竭对慢性阻塞性肺疾病(COPD)急性加重频率以及严重程度的影响。方法:选择COPD患者274例,其中无右心衰竭患者194例,合并右心衰竭患者80例,随访1年,记录其急性加重事件发生情况。结果: 合并右心衰竭组急性加重次数明显高于无右心衰竭组\[(1.33±0.49)次/年 vs (0.86±0.25)次/年,P<0.05\]。合并右心衰竭组急性加重严重程度(血气分析、呼吸困难评分、不良事件和严重不良事件)显著高于无右心衰竭组(均P<0.05)。结论 :合并右心衰竭可能是COPD发生多次和严重急性加重的重要危险因素。
    英文摘要:
          Objective: To explore the effect of comorbid right heart failure on the frequency and the severity of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Methods: 274 cases of COPD were enrolled in this study, including 194 patients without heart failure and 80 patients with right heart failure. All cases were followed up for 1 year and their acute exacerbations were recorded. Results: The frequency of acute exacerbations in the combined right heart failure group (1.33±0.49) was significantly higher than that in the non-right heart failure group (0.86±0.25,P<0.05). The severity of acute exacerbations in the combined right heart failure group was also significantly greater than that in the non-right heart failure group (such as blood gas analysis, dyspnea score, adverse events and severe adverse events, P<0.05). Conclusion: Right heart failure may be an risk factor for multiple and severe AECOPD.