林祥兵.合并右心衰竭对慢性阻塞性肺疾病急性加重频率及严重程度的影响[J].内科急危重症杂志,2019,25(1):45-47
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| DOI：10.11768/nkjwzzzz20190114 |
| 中文关键词: 慢性阻塞性肺疾病 急性加重 右心衰竭 |
| 英文关键词: |
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| 中文摘要: |
| 目的：探讨合并右心衰竭对慢性阻塞性肺疾病(COPD)急性加重频率以及严重程度的影响。方法:选择COPD患者274例，其中无右心衰竭患者194例，合并右心衰竭患者80例，随访1年，记录其急性加重事件发生情况。结果： 合并右心衰竭组急性加重次数明显高于无右心衰竭组\[(1.33±0.49)次/年 vs (0.86±0.25)次/年，P＜0.05\]。合并右心衰竭组急性加重严重程度（血气分析、呼吸困难评分、不良事件和严重不良事件）显著高于无右心衰竭组（均P＜0.05）。结论 ：合并右心衰竭可能是COPD发生多次和严重急性加重的重要危险因素。 |
| 英文摘要: |
| Objective: To explore the effect of comorbid right heart failure on the frequency and the severity of acute exacerbations of chronic obstructive pulmonary disease (AECOPD). Methods: 274 cases of COPD were enrolled in this study, including 194 patients without heart failure and 80 patients with right heart failure. All cases were followed up for 1 year and their acute exacerbations were recorded. Results: The frequency of acute exacerbations in the combined right heart failure group (1.33±0.49) was significantly higher than that in the non-right heart failure group (0.86±0.25,P<0.05). The severity of acute exacerbations in the combined right heart failure group was also significantly greater than that in the non-right heart failure group (such as blood gas analysis, dyspnea score, adverse events and severe adverse events, P<0.05). Conclusion: Right heart failure may be an risk factor for multiple and severe AECOPD. |
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