• 重症监护室中侵袭性肺曲霉菌病的诊断标准:因人而异
  • 张英芳.重症监护室中侵袭性肺曲霉菌病的诊断标准:因人而异[J].内科急危重症杂志,2022,28(5):361-367
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    DOI:10.11768/nkjwzzzz20220503
    中文关键词:  肺曲霉菌病  诊断标准
    英文关键词:
    基金项目:国家自然科学基金(No:81870072)
    作者单位E-mail
    张英芳 北京大学医学部中日友好临床医学院 xuehuaalice@126.com 
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    中文摘要:
          侵袭性肺曲霉菌病(IPA)在重症监护室(ICU)患者中发病率、病死率高。因此,制定足够灵敏、特异的诊断标准辅助早期识别IPA对改善患者的预后至关重要。目前关于IPA的诊断标准主要包括欧洲癌症研究和治疗组织/侵袭性真菌感染协作组织提出的诊断标准(以下简称EORTC/MSG标准)、ICU患者诊断标准、Bulpa标准、流感相关性肺曲霉菌病(IAPA)诊断标准和国际心肺移植学会(ISHLT)针对心肺移植术后患者的诊断标准。本文主要对以上标准的适用人群、主要特点及局限性进行阐述,以期临床医生能够在临床诊疗中针对不同的患者选择个体化的诊断标准。
    英文摘要:
          Invasive pulmonary aspergillosis (IPA) is an important cause of morbidity and mortality in intensive care unit (ICU). Therefore, an appropriate diagnostic criterion with adequate sensitivity and specificity is needed to identify IPA as early as possible and thus to improve the prognosis ultimately. Five diagnostic criteria have been proposed for IPA, namely the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium (EORTC/MSG) criteria, ICU criteria, Bulpa criteria, influenza associated pulmonary aspergillosis(IAPA) criteria and International Society of Heart and Lung(ISHLT) criteria. This review is mainly elaborating on the appropriate population, main characteristics and limitations of the above criteria, so that clinicians can select individual diagnostic criteria for different patients in clinical practice.