李思雯.肝细胞癌生物标志物的研究进展：对于临床诊断及预后的意义[J].内科急危重症杂志,2023,29(1):6-10
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| DOI：10.11768/nkjwzzzz20230102 |
| 中文关键词: 肝细胞癌 蛋白质生物标志物 炎症生物标志物 MicroRNAs 环状RNA |
| 英文关键词: |
| 基金项目:国家自然科学基金面上项目（No：82173313;No：81871911） |
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| 中文摘要: |
| 摘要 肝细胞癌（HCC）是2020年癌症死亡的第三大原因，也是全球第六大常见癌症。大多数肝癌患者在就诊时已发展为晚期癌症，尽管HCC发病率很高，但对于晚期患者的治疗方案并不多，所以提高HCC患者的早期发现率非常必要。本文总结HCC中已发现的生物标志物，希望能够为肝癌的早期诊断和预后判断提供新的视角。 |
| 英文摘要: |
| Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths in 2020 and the sixth most common cancer worldwide. Most HCC patients have developed advanced cancer by the time they are diagnosed. Despite the high incidence of HCC, there are few treatment options for patients with advanced disease, therefore it is essential to improve the early detection and prognosis of HCC patients. Biomarkers are a relatively simple and noninvasive detection technique that can be of great help in the diagnosis and prognosis of the disease. However, there are still no ideal biomarkers in HCC, therefore, the discovery and understanding of HCC biomarkers is important in the clinical management process. In this review, we summarize the biomarkers that have been identified in HCC, hoping to provide new perspectives for the early diagnosis and prognosis of HCC. |
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