• Stanford B型急性主动脉夹层947例临床分析
  • 冯美干.Stanford B型急性主动脉夹层947例临床分析[J].内科急危重症杂志,2023,29(1):14-17
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    DOI:10.11768/nkjwzzzz20230104
    中文关键词:  急性主动脉夹层  Stanford分型  腔内覆膜支架修复术
    英文关键词:
    基金项目:国家自然科学基金资助项目(No:81873518)
    作者单位E-mail
    冯美干 华中科技大学同济医学院附属同济医院 xmguo@tjh.tjmu.edu.cn 
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    中文摘要:
          摘要 目的:探讨Stanford B型急性主动脉夹层(AAD)的临床特点及不同治疗方式对预后的影响。方法:回顾性分析947例Stanford B型主动脉夹层患者的临床资料,根据治疗方式分为非介入手术组(单纯药物治疗457例)和介入手术组(490例)。统计并比较2组院内死亡率。结果:947例患者中,男789例,平均年龄(55.9±12.6)岁,女158例,平均年龄(56.8±11.4)岁。住院死亡40例(4.22%);其中非介入手术组死亡39例;介入手术组死亡1例;非介入手术组院内病死率明显高于介入手术组(8.53% vs 0.20%,P<0.01)。结论:Stanford B型AAD患者病情急,进展快,死亡风险大,尽早确诊并行适宜的介入手术治疗可明显提高患者的生存率。
    英文摘要:
          Abstract Objective: To investigate the clinical characteristics of Stanford type B acute aortic dissection (AAD) and the effect of different treatments on prognosis. Methods: The clinical data of 947 patients with Stanford B type aortic dissection were analyzed retrospectively. The patients were divided into two groups: non-interventional operation group (drug therapy only, 457 cases) and interventional operation group (490 cases). The mortality rates of the two groups were compared. Results: A total of 947 patients were enrolled, including 789 males with an average age of 55.9±12.6 years and 158 females with the mean age of 56.8±11.4 years. There were 40 in-hospital deaths, and the total mortality rate was 4.22%. A total of 39 cases died in the non-interventional operation group with the mortality rate being 8.53%. One case died in the interventional operation group with the mortality rate being 0.20%. The in-hospital mortality rate in the non-interventional operation group was significantly higher than that in the interventional operation group (P< 0.001). Conclusion: Patients with Stanford type B AAD are at high risk of death due to rapid progression and rapid onset. Early diagnosis and appropriate interventional operation can apparently improve the survival rate of patients.