颈内动脉狭窄伴未破裂颅内动脉瘤患者的临床特点及危险因素

张斌.颈内动脉狭窄伴未破裂颅内动脉瘤患者的临床特点及危险因素[J].内科急危重症杂志,2023,29(1):23-25

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DOI：10.11768/nkjwzzzz20230106

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作者	单位	E-mail
张斌	首都医科大学附属北京友谊医院	13621184808@163.com

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中文摘要:

摘要目的：探讨颈内动脉狭窄伴未破裂颅内动脉瘤患者的动脉瘤特点及危险因素。方法：选择颈内动脉狭窄患者120例，其中合并未破裂颅内动脉瘤患者10例为观察组，其余110例患者为对照组。分析观察组患者的动脉瘤特点及危险因素。结果：观察组共检测到动脉瘤11个，1例（10%）患者存在2个动脉瘤，其余均为单一动脉瘤；1例（10%）患者动脉瘤直径为7mm，9例（90%）患者动脉瘤直径为1~4mm；动脉瘤位于椎基底动脉尖1例（10%），位于颈内动脉系统9例（90%）；动脉瘤与狭窄位于同一血管者有8例（80%）；位于不同血管者有2例（20%）；2组年龄、颈内动脉狭窄程度以及合并糖尿病、高血压、高脂血症、冠心病、饮酒史、吸烟史、缺血性卒中史等比较，差异无统计学意义（P均＞0.05）；经多因素Logistic回归分析显示，女性存在动脉瘤更多见 [r=5.111,95%C1 1.340~19.492),P=0.017]。结论：颈内动脉狭窄伴未破裂颅内动脉瘤多为单一动脉瘤、动脉瘤直径多＜5mm、多位于颈内动脉系统且动脉瘤与狭窄位于同一血管者较多见；女性存在动脉瘤更多见，临床应加以重视。

英文摘要:

Abstract Objective: To investigate the characteristics and risk factors of internal carotid artery stenosis with un-ruptured intracranial aneurysm. Methods: Totally, 120 patients with internal carotid artery stenosis were selected, including 10 patients with un-ruptured intracranial aneurysms as the observation group and the rest 110 patients as the control group. The characteristics and risk factors of aneurysms in the observation group were analyzed. Results: A total of 11 aneurysms were detected in the observation group. One patient (10%) had 2 aneurysms, and the rest had single aneurysm. The diameter of aneurysm was 7 mm in 1 patient (10%) and 1-4 mm in 9 patients (90%). The aneurysms were located at the apex of the vertebrobasilar artery in 1 case (10%), and in the internal carotid artery system in 9 cases (90%). Eight cases (80%) had aneurysm and stenosis located in the same vessel. Two cases (20%) were not located in the same vessel. There was no significant difference between the two groups in age, degree of internal carotid artery stenosis, and the proportion of patients with diabetes, hypertension, hyperlipidemia, coronary heart disease, drinking history, smoking history, and ischemic stroke history (P> 0.05). Multivariate logistic regression analysis showed that aneurysms were more common in women. Conclusions: Internal carotid artery stenosis with un-ruptured intracranial aneurysms is more common in patients with single aneurysm, aneurysm diameter less than 5mm, located in internal carotid artery system, and aneurysm and stenosis located in the same vessel. Un-ruptured intracranial aneurysm is more common in women.