• 肾综合征出血热患者血浆细胞因子的动态变化
  • 任丹凤.肾综合征出血热患者血浆细胞因子的动态变化[J].内科急危重症杂志,2023,29(3):181-184
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    DOI:10.11768/nkjwzzzz20230302
    中文关键词:  肾综合征出血热  细胞因子
    英文关键词:
    基金项目:国家自然科学基金面上项目(No:8207032750)
    作者单位E-mail
    任丹凤 西安交通大学第一附属医院感染科 heyingli2000@163.com 
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    中文摘要:
          肾综合征出血热(HFRS)是由汉坦病毒(hantavirus)引起的以啮齿类动物为主要传染病的自然疫源性疾病,我国是HFRS的高发地区之一,其长期危害我国人民的生命健康。研究表明过度活化的免疫应答和炎症反应引起的“细胞因子风暴”是导致HFRS致病的机制之一。本文拟对HFRS患者中各种细胞因子的动态变化进行综述。
    英文摘要:
          Abstract Hemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by Hantavirus, which mainly affects rodents. China is one of the areas with high incidence of HFRS, which endangers the life and health of Chinese people for a long time. Studies have shown that overactivated immune responses and "cytokine storms" caused by inflammatory responses are one of the mechanisms responsible for the pathogenesis of HFRS. This paper intends to review the dynamic changes of various cytokines in patients with HFRS.