宋君.如何评估和实现糖尿病缓解[J].内科急危重症杂志,2023,29(4):265-267
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| DOI：10.11768/nkjwzzzz20230401 |
| 中文关键词: 糖尿病缓解 生活方式 药物治疗 代谢手术 |
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| 中文摘要: |
| 长期以来，人们一直认为2型糖尿病是进展性终身性疾病，需长期药物治疗。然而，近年来研究表明，部分糖尿病患者经生活方式干预、药物或代谢手术治疗后可免于药物治疗，血糖仍可处于达标或正常状态，即实现糖尿病缓解。根据2021年美国糖尿病学会（ADA）和欧洲糖尿病学会（EASD）联合发布的《糖尿病缓解专家共识》及《缓解2型糖尿病中国专家共识》将停用降糖药物至少3个月后糖化血红蛋白<6.5%定义为糖尿病缓解。目前实现糖尿病缓解的方法包括生活方式干预、药物及代谢手术。糖尿病缓解对患者、家庭及整个社会意义重大，然而并非所有患者均可实现糖尿病缓解。充分评估糖尿病缓解的条件，将有助于更好地实现和维持糖尿病缓解。临床上应加强对已实现糖尿病缓解患者的管理，定期随访，长期监测，以及时发现复发，改善预后。 |
| 英文摘要: |
| Abstract Type 2 diabetes mellitus (T2DM) is a progressive and lifelong disease characterized by hyperglycemia, which requires long-time treatment. Recently, accumulated studies have shown that some diabetes patients can achieve diabetes remission by lifestyle intervention, medication and metabolic surgery. According to the Expert Consensus jointly issued by the American Diabetes Association (ADA) and the European Diabetes Association (EASD) in 2021 and the Chinese Expert Consensus on Type 2 Diabetes Remission, diabetes remission is defined as HBA1c <6.5% after discontinuation of hypoglycemic agents for at least three months. Diabetes remission is of great significance to patients, families, and society. However, not all patients can achieve diabetes remission. Early recognition of the characteristics of diabetes remission will facilitate to achieve and maintain diabetes remission. In clinical practice, long-term monitoring and regular follow-up should be conducted in patients with diabetes remission to discover recurrence in time, prevent and delay the development of complications, improve the quality of life and the prognosis. |
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