卓玲.髓外浆细胞瘤治疗的研究进展[J].内科急危重症杂志,2024,30(6):561-564
扫码阅读全文
|
| DOI：10.11768/nkjwzzzz.20240617 |
| 中文关键词: 多发性骨髓瘤 髓外病变 治疗 |
| 英文关键词: |
| 基金项目:宜昌市医疗卫生研究项目（A23-1-028） |
|
| 摘要点击次数: 70 |
| 全文下载次数: 92 |
| 中文摘要: |
| 摘要 髓外浆细胞瘤(EMD) 属于浆细胞肿瘤的一种，是浆细胞瘤穿透骨皮质或在骨骼以外部位形成的软组织肿物，具有高侵袭性和预后差的特性。目前EMD的发病机制尚不明确，治疗上尚无统一标准，可选择蛋白酶体抑制剂、免疫调节剂、单克隆抗体、造血干细胞移植（ASCT）、嵌合抗原T细胞疗法（CAR-T）、靶向药物等。本文将就有关EMD治疗的最新研究进展进行概述，以期为临床工作提供参考。 |
| 英文摘要: |
| Abstract Extramedullary disease (EMD) is a kind of plasmacytoma, which is a soft tissue tumor formed by plasmacytoma penetrating the bone cortex or outside the bone. It has the characteristics of high invasion and poor prognosis. At present, the pathogenesis of EMD is not clear, and there is no unified standard for treatment. Proteasome inhibitors combined with immunomodulators, monoclonal antibodies, autologous hematologist stem cell transplantion, chimeric antigen receptor T-cell (CAR-T）, and targeted drugs can be selected for treatment. This article will summarize the latest research progress on EMD treatment to provide a reference for clinical work. |
|
|
|
|
