汪道文.血管痉挛性心绞痛诊断与治疗共识和最新进展[J].内科急危重症杂志,2025,31(1):1-20
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| DOI：10.11768/nkjwzzzz20250101 |
| 中文关键词: 血管痉挛性心绞痛 冠状动脉痉挛 炎症 心肌炎症 抗炎治疗 |
| 英文关键词: |
| 基金项目:国家自然科学基金（82330010，82241034，82370507）；湖北省顶尖人才计划及同济医院优秀青年基金滚动资助（24 2KYC13057 04） |
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| 中文摘要: |
| 摘要 血管痉挛性心绞痛（VSA）是由心肌表层冠状动脉局部或弥漫性痉挛所致的心绞痛，是一类严重威胁人类健康的临床疾病。虽然国内外已有多部指南或共识发表，但在诊断和治疗方面多沿用传统方法，既不能改善VSA患者易误诊和漏诊的现状，也无法减少其心血管事件风险，尤其是对VSA的本质认识不足。本文结合最新研究结果，提出心肌炎症是VSA的重要原因和治疗靶点这一新理念，重点介绍了针对心肌炎症的检查与干预药物在VSA诊治中的最新进展，以期提高VSA的救治水平。 |
| 英文摘要: |
| Abstract Vasospastic angina (VSA) is a life-threatening disease caused by local or diffuse spasm of the superficial coronary arteries. Several guidelines or consensuses related to VSA have been published in the past, but traditional methods have been maintained for its diagnosis and treatment. Therefore, the risk of missed diagnosis, misdiagnosis and the related cardiovascular events have not been improved. In this consensus, we put forward that myocardial inflammation is an important cause and therapeutic target of VSA, and emphasize on the progression of examination and therapeutic drugs related to inflammation in the diagnosis and treatment of VSA, in order to improve the capability for the treatment of VSA. |
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