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苏凡.绝经后女性严重冠脉病变的危险因素分析[J].内科急危重症杂志,2025,31(4):335-337
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| DOI：10.11768/nkjwzzzz20250409 |
| 中文关键词: 绝经女性 严重冠脉病变 Gensini评分 |
| 英文关键词: |
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| 摘要点击次数: 9 |
| 全文下载次数: 15 |
| 中文摘要: |
| 摘要 目的：探讨绝经后女性严重冠脉病变的危险因素。方法：收集156例绝经后女性冠心病患者，依据 Gensini积分,分为对照组(<45分)127例和严重冠脉病变组(≥45分)29例，比较2组临床资料，多因素分析严重冠脉病变的危险因素。结果：严重冠脉病变组高龄、血糖化血红蛋白、B型脑钠肽（BNP）和超敏C反应蛋白（hs-CRP）水平高于对照组（P均<0.05），是严重冠脉病变的可能危险因素。Logistic回归分析表明hs-CRP升高的患者冠脉严重病变的发生风险增加1.126倍（OR=1.126,95%CI:1.035~1.225），血清三碘甲状腺原氨酸（T3）水平的升高可能降低冠脉严重病变的发生风险（OR=0.236,95%CI:0.063~0.883）。结论：血清hs-CRP、糖化血红蛋白是绝经后女性严重冠脉病变的危险因素，血清T3水平的升高可能是女性严重冠脉病变的保护因素。加强对这些危险因素的常规筛查，可能有助于改善女性冠心病预后。 |
| 英文摘要: |
| Abstract Objective: To explore the risk factors for severe coronary artery disease in postmenopausal women. Methods: A total of 156 postmenopausal women with coronary heart disease were enrolled. Based on the Gensini score, the patents were divided into the control group (127 cases, <45 points) and the severe coronary artery disease group (29 cases, ≥45 points). Clinical data were compared between the two groups, and multivariate analysis was performed to identify risk factors for severe coronary artery disease. Results: In the severe coronary artery disease group, the proportion of elderly patients, as well as the levels of glycosylated hemoglobin, B-type natriuretic peptide (BNP), and high-sensitivity C-reactive protein (hs-CRP) were higher than those in the control group (all P< 0.05), which may be risk factors for severe coronary artery disease. Logistic regression analysis showed that patients with elevated hs-CRP had a 1.126-fold increased risk of severe coronary artery disease (OR= 1.126, 95%CI: 1.035-1.225), while elevated serum triiodothyronine (T3) levels might reduce the risk of severe coronary artery disease (OR= 0.236, 95%CI: 0.063-0.883). Conclusion: Serum hs-CRP and glycosylated hemoglobin are risk factors for severe coronary artery disease in postmenopausal women, while elevated serum T3 levels may be a protective factor against severe coronary artery disease in women. Strengthening routine screening for these risk factors may help improve the prognosis of coronary heart disease in women. |
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