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李博.青年急性缺血性脑卒中发病危险因素分析[J].内科急危重症杂志,2025,31(4):356-360
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| DOI：10.11768/nkjwzzzz20250414 |
| 中文关键词: 急性缺血性脑卒中 动脉狭窄 危险因素 狭窄程度 高脂血症 糖尿病 |
| 英文关键词: |
| 基金项目:河北省卫生健康委员会课题（20220453） |
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| 摘要点击次数: 10 |
| 全文下载次数: 12 |
| 中文摘要: |
| 摘要 目的：探讨青年急性缺血性脑卒中（AIS）发病的危险因素及其与动脉狭窄及狭窄程度的相关性。方法：选取青年AIS患者228例作为研究组，另选取同期健康体检青年228例作为对照组。收集2组临床资料，分析青年AIS发病危险因素，及其与动脉狭窄及狭窄程度的相关性。结果：Logistic回归分析显示，肥胖、饮酒、吸烟、高钠饮食、高血压、高脂血症、糖尿病、平均每周工作时间、工作压力、偏头痛是青年AIS发病的独立危险因素（OR分别为7.242、5.079、5.461、4.071、10.675、8.329、11.485、7.885、7.596、3.502，P均＜0.05）；可视化森林图显示，以上10项均为正相关危险因素（P均＜0.05）；不同年龄分层中，伴动脉狭窄患者这10项因素比例高于不伴动脉狭窄患者（P均＜0.05）；但不同程度动脉狭窄患者间比较，差异无统计学意义（P均＞0.05）；Spearman相关性分析显示，以上10项危险因素与动脉狭窄呈正相关（P均＜0.05），但与动脉狭窄程度无明显相关性（P均＞0.05）。结论：肥胖、饮酒、吸烟、高钠饮食、高血压、高脂血症、糖尿病、平均每周工作时间、工作压力、偏头痛与动脉狭窄呈正相关，是青年AIS发病危险因素。 |
| 英文摘要: |
| Abstract Objective: To investigate the risk factors for the onset of acute ischemic stroke (AIS) in young adults and their correlation with arterial stenosis and the degree of stenosis. Methods: A total of 228 young adults with AIS were selected as the study group, and 228 young individuals who underwent healthy physical examinations during the same period were selected as the control group. Clinical data from both groups were collected to analyze the risk factors for the onset of AIS in young adults and their correlation with arterial stenosis and the degree of stenosis. Results: Logistic regression analysis revealed that obesity, alcohol consumption, smoking, high-sodium diet, hypertension, hyperlipidemia, diabetes, average weekly working hours, work pressure, and migraine were independent risk factors for the onset of AIS in young adults (ORs were 7.242, 5.079, 5.461, 4.071, 10.675, 8.329, 11.485, 7.885, 7.596, and 3.502, respectively; all P<0.05). The visualized forest plot indicated that all 10 factors were positively correlated risk factors (all P<0.05). In different age groups, the proportion of these 10 factors in patients with arterial stenosis was higher than that in patients without arterial stenosis (P<0.05), However, there was no significant difference between patients with different degrees of arterial stenosis (P>0.05). Spearman correlation analysis showed that all 10 risk factors were positively correlated with arterial stenosis (all P<0.05), but not significantly correlated with the degree of arterial stenosis (all P>0.05). Conclusions: Obesity, alcohol consumption, smoking, high-sodium diet, hypertension, hyperlipidemia, diabetes, average weekly working hours, work pressure, and migraine are positively correlated with arterial stenosis and are risk factors for the onset of AIS in young adults. |
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