薛晓.亟需破解静脉血栓栓塞症合并活动性出血的“矛盾”[J].内科急危重症杂志,2025,31(5):395-400
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DOI:10.11768/nkjwzzzz20250502 |
中文关键词: 静脉血栓栓塞症 活动性出血 风险评估 抗凝治疗 出血管理 临床决策 |
英文关键词: |
基金项目:北京市卫生健康委首都卫生发展科研专项(首发2024-2-2067) |
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中文摘要: |
摘要 静脉血栓栓塞症(VTE)包括深静脉血栓形成(DVT)和肺血栓栓塞症(PTE),抗凝为其治疗基础,但抗凝可能诱发出血,导致“血栓-出血”的治疗矛盾。本文系统回顾VTE合并活动性出血的规范化评估与个体化治疗策略,探讨各风险预测模型在临床评估中的应用,并探讨了动态风险评估模型、新型抗凝药物及人工智能辅助决策等的临床应用。为其治疗基础,但抗凝可能诱发出血,导致“血栓-出血”的治疗矛盾。本文系统回顾VTE合并活动性出血的规范化评估与个体化治疗策略,探讨各风险预测模型在临床评估中的应用,并探讨了动态风险评估模型、新型抗凝药物及人工智能辅助决策等的临床应用。 |
英文摘要: |
Abstract Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE). Anticoagulation is the cornerstone of its treatment; however, anticoagulation may induce bleeding, leading to the therapeutic dilemma of "thrombus-bleeding". This article systematically reviews the standardized assessment and individualized treatment strategies for VTE complicated with active bleeding, explores the application of various risk prediction models in clinical assessment, and discusses the clinical applications of dynamic risk assessment models, novel anticoagulants, and artificial intelligence-assisted decision-making. |
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