张一笑.肿瘤合并静脉血栓栓塞症的风险评估、预防及处理[J].内科急危重症杂志,2025,31(5):401-408
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DOI:10.11768/nkjwzzzz20250503 |
中文关键词: 肿瘤 静脉血栓栓塞症 发病机制 风险评估工具 预防策略 治疗原则 |
英文关键词: |
基金项目:国家重点研发计划"常见多发病防治研究"重点专项(2023YFC2507202) |
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中文摘要: |
摘要 静脉血栓栓塞症(VTE)包括深静脉血栓形成与肺血栓栓塞症,是恶性肿瘤患者常见且严重的并发症之一。VTE显著增加肿瘤患者的死亡风险和医疗负担,是继肿瘤本身之后的第二大死亡原因。随着抗肿瘤治疗方法的不断进步,患者生存时间延长,VTE发生率亦呈上升趋势。本文系统论述了肿瘤合并VTE的发病机制、风险评估工具、预防策略及治疗原则等方面的研究进展,并提出未来有待探索的问题。 |
英文摘要: |
Abstract Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a common and serious complication in patients with malignancies. VTE significantly increases both mortality and healthcare burden in cancer patients, representing as the second leading cause of death. With ongoing advancements in anticancer therapies and prolonged patient survival, the incidence of VTE is also increasing. This review provides a comprehensive overview of advances in the pathogenesis, risk assessment models, prevention, and treatment approaches for cancer-associated VTE, and highlights unresolved issues to be addressed in future research. |
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