|
王晓慧.妊娠相关静脉血栓栓塞症的防治[J].内科急危重症杂志,2025,31(5):415-421
|
| DOI：10.11768/nkjwzzzz20250505 |
| 中文关键词: 妊娠 静脉血栓栓塞症 预防 诊断 治疗 |
| 英文关键词: |
| 基金项目: |
|
| 摘要点击次数: 18 |
| 全文下载次数: 20 |
| 中文摘要: |
| 摘要 静脉血栓栓塞症（VTE）是孕产妇死亡的主要原因之一，严重威胁母婴健康与生命安全。妊娠期独特的生理性高凝状态、血流动力学改变及血管损伤等因素共同构成了血栓形成的病理生理基础。然而，由于妊娠期VTE的临床表现常不典型，且诊断性检查的应用受到限制，给临床及时、准确的诊治带来了巨大挑战。若能对孕产妇进行贯穿妊娠期及产褥期的全程动态风险评估，并据此采取个体化的预防与管理策略，将极大改善临床结局。本文旨在系统阐述妊娠相关VTE的流行病学特征、病理生理机制、诊断难点、治疗策略及风险分层与预防措施的研究进展，以期为临床医师深化对该疾病的认识、提升规范化防治能力提供参考与依据。 |
| 英文摘要: |
| Abstract Venous thromboembolism (VTE) is one of the leading causes of maternal mortality, posing a serious threat to the health and life of both mother and infant. The unique physiological hypercoagulable state, hemodynamic changes, and vascular injury during pregnancy constitute the pathophysiological basis for thrombosis. However, the timely and accurate diagnosis and treatment of VTE in pregnancy face significant challenges due to its often atypical clinical manifestations and limitations in the use of diagnostic tests. The ability to conduct continuous and dynamic risk assessment for pregnant and postpartum women throughout pregnancy and the puerperium, and to adopt individualized prevention and management strategies accordingly, can greatly improve clinical outcomes. This article aims to systematically review the research progress on the epidemiological characteristics, pathophysiological mechanisms, diagnostic difficulties, treatment strategies, and risk stratification with preventive measures for pregnancy-associated VTE, with the goal of providing a reference for clinicians to deepen their understanding of this disease and enhance their capabilities for standardized prevention and treatment. |
|
|
|
|
