右美托咪定对全麻患者i-gel喉罩插入时应激反应的影响
The stress response effects in the i-gel anesthesia laryngeal mask insertion on the anesthesia patients by the dexmedetomidine

李敏仙,顾颖红.右美托咪定对全麻患者i-gel喉罩插入时应激反应的影响[J].内科急危重症杂志,2015,21(3):

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英文关键词:Dexmedetomidine laparoscopy anesthesia i-gel laryngeal mask stress response

基金项目:海南省卫生厅课题：喉罩无肌松技术在老年患者股骨头置换术中的应用、立项依据，编号：琼卫2011-45

作者	单位	E-mail
李敏仙	海南医学院附属医院麻醉科	limx4203@163.com
顾颖红	海南医学院附属医院麻醉科	guyh4203@163.com

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中文摘要:

目的：探讨右美托咪定对全麻患者i-gel喉罩插入时应激反应的影响。方法：择期行腹腔镜下手术患者120例根据随机抽签原则分为治疗组与对照组各60例,两组都给予喉罩插入下全麻,在麻醉诱导与维持期,治疗组给予右美托咪定辅助干预,对照给予同剂量生理盐水辅助干预。结果：两组的麻醉时间、呼吸恢复时间、呼之睁眼时间和拔出喉罩时间对比差异都无统计学意义(P>0.05)。T1时间点治疗组的OAA/S评分与NI指数明显下降,与对照组对比差异明显(P<0.05),与TO时间点对比差异也有统计学意义(P<0.05),T2时间点及其以后两组NI值及OAA/S评分对比差异无统计学意义。治疗组的喉罩插入应激反应发生率为1.3%,对照组为10.0%,治疗组的喉罩插入应激反应发生率明显低于对照组(P<0.05)。结论：腹腔镜下全麻患者采用i-gel喉罩插入具有很好的麻醉效果,而右美托咪定的应用能增强镇静作用,减少应激反应的发生,为患者提供安全有效舒适的麻醉。

英文摘要:

Objective: To investigate the stress response effects in the i-gel anesthesia laryngeal mask insertion on the anesthesia patients by the dexmedetomidine. Methods: 120 elective laparoscopic surgery patients based on the principle of a random draw were equally divided into the treatment group and the control group, both groups were given laryngeal mask insertion under general anesthesia, In the induction and maintenance of anesthesia, the treatment group were given the dexmedetomidine aid intervention, and the control group were given the same dose of saline aid intervention. Results: The anesthesia time, recovery time breathing, eye opening and pull out the laryngeal mask and call time in the two groups compared the differences were not statistically significant (P>0.05). In the T1 time, the OAA/ S scores and NI index in the treatment group were decreased significantly different compared with the control group (P<0.05), and compared with the TO time were also statistically significant differences (P<0.05), In the T2 time point, the OAA/ S scores and NI index in the two groups compared difference were not statistically significant. The laryngeal mask insertion stress response rate in the treatment group were 1.3%, so that were 10.0% in the control group, and the laryngeal mask insertion stress response rate in the treatment group were significantly lower than the control group (P<0.05). Conclusion: Laparoscopic anesthesia patients with i-gel insertion of laryngeal mask has good anesthesia results, dexmedetomidine application can enhance the sedative effect, reduce the incidence of stress response, and provide patients with safe, effective and comfortable anesthesia .